tumor suppressing gene การใช้

Decreased hypermethylation patterns reveal a transcriptionally accessible promoter region, allowing for increased expression of the tumor suppressing genes.
The hypermethylation in the promoter regions of the tumor suppressing genes APC and RASSF1A are common epigenetic markers for cancer.
The gene, which appears to work in a way different from previously discovered tumor suppressing genes, has been found in advanced cancers of the brain, breast, prostate and kidney, and it may be at work in others as well.
"Clinical development of hundreds of potential disease-treating drugs have been abandoned after rodent studies have shown them to be potential carcinogens _ studies that might have had a different outcome if rodents possessed two functional copies of " the tumor suppressing gene, Killian said.